TABLE 4a.
Associations between maternal iron status at early and mid-pregnancy with systolic blood pressure in late pregnancy (multivariable linear regression).
| Gestational age | Predictor | Systolic blood pressure (mmHg) |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Model 1 (n = 190) |
Model 2 (n = 189) |
Model 3 |
||||||||
| B | 95% CI | p | B | 95% CI | p | B | 95% CI | p | ||
| < 18 weeks | Hb (g/dL) | −0.46 | −1.46, 0.53 | 0.358 | −0.87 | −1.87, 0.13 | 0.089 | - | - | - |
| Fer (μg/L) | −0.01 | −0.02, 0.01 | 0.376 | −0.01 | −0.02, 0.01 | 0.273 | - | - | - | |
| sTfR (mg/L) | 0.04 | −0.15, 0.22 | 0.709 | 0.08 | −0.10, 0.26 | 0.407 | - | - | - | |
| Model 1 (n = 189) | Model 2 (n = 188) | Model 3 (n = 188) | ||||||||
| 22 weeks | Hb (g/dL) | −1.04 | −2.06, -0.02 | 0.046 | −1.10 | −2.11, -0.09 | 0.033 | −0.75 | −1.59, 0.09 | 0.081 |
| Fer (μg/L) | −0.01 | −0.04, 0.02 | 0.660 | −0.02 | −0.04, 0.01 | 0.310 | −0.01 | −0.03, 0.02 | 0.695 | |
| sTfR (mg/L) | −0.03 | −0.33, 0.27 | 0.858 | −0.03 | −0.32, 0.28 | 0.831 | −0.07 | −0.31, 0.17 | 0.566 | |
CI, confidence interval; Hb, haemoglobin; Fer, serum ferritin; sTfR, soluble transferrin receptor. Associations were assessed with multivariable linear regression, B-values and 95% confidence intervals. Model 1 is adjusted for maternal age and living standards measure (socio-economic status); model 2 is adjusted additionally for gestational age, CRP and maternal BMI at baseline, HIV status throughout pregnancy and aspirin prescription during mid-pregnancy; model 3 is adjusted additionally for blood pressure at ± 22 weeks’ gestation. p < 0.05 was considered significant and p between 0.05 and 0.08 had a tendency towards significance.