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. 2024 Jun 19;15:1355269. doi: 10.3389/fphar.2024.1355269

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Copyright © 2024 Lin, Yang, Wang, Huang, Wang, Chen, Xu, Cai, Khan, Liu and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Single-cell transcriptomic analysis of TME-Met PI genes in gastric cancer. (A, B) Uniform manifold approximation and projection (UMAP) plots showing main clusters and cell-types in single-cell gastric cancer dataset (GSE112302), colored by cluster (A) and (B) cell type. (C) Bubble plot shows the expression levels of top 3 marker genes in each cell-type for GSE112302 dataset. (D) UMAP plots displaying expression patterns of cell-specific marker genes for each cell-type in GSE112302 dataset. (E) The bubble plot depicting the expression levels of TME-Met PI genes in all cell types in GSE112302 dataset. (F, G) UMAP plots showing main clusters and cell-types in single-cell gastric cancer dataset (GSE167297), colored by cluster (F) and (G) cell type. (H) UMAP plots displaying expression patterns of cell-specific marker genes for each cell-type in GSE167297 dataset. (I) The bubble plot depicting the expression levels of TME-Met PI genes in all cell types in GSE167297 dataset.