Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Jun 19;15:1393746. doi: 10.3389/fphar.2024.1393746

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2024 Conte, Mantuano, Boccanegra, Imbrici, Dinoi, Lenti, Cappellari, Cappetta, De Angelis, Berrino, Gordish-Dressman, Bianchini, Aramini, Allegretti, Liantonio and De Luca.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Hz50 of isolated EDL muscle. Values for Hz50, a contractile index related to calcium homeostasis indicating the frequency at which 50% of maximal isometric specific tetanic force (sP0) is produced, measured in extensor digitorum longus (EDL) muscles isolated from ADULT, AGED + vehicle, AGED + branched-chain amino acids (AGED + BCAAs), AGED + branched-chain amino acids +2 L-alanine (AGED + BCAAs + 2ALA), and AGED + branched-chain amino acids + L-alanyl-L-alanine (AGED + BCAAs + Di-ALA). All values are expressed as mean ± SEM from a number of 6/8 mice in each group. A statistically significant difference was found by unpaired Student’s t-test for AGED + vehicle vs. ADULT mice (p < 0.03). A statistically significant difference among AGED mice groups was found by one-way ANOVA (F = 8.9, p = 0.0003). Dunnett’s post hoc test, used to compare each mixture-treated group to the vehicle group, is as follows: °vs. AGED + vehicle (0.0002 < p < 0.03). The recovery score toward the ADULT value, calculated for each treated group, is indicated above the bars.