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. 2024 Jun 19;11:1387956. doi: 10.3389/fnut.2024.1387956

Figure 2.

Figure 2

The entire set of matched differential metabolic pathways between human milk of Cluster I and other clusters based on p values from pathway enrichment analysis and pathway impact values derived from pathway topology analysis. Each node represents a distinct metabolism pathway. It was observed that Cluster I and the other two clusters exhibited significant differences in multiple metabolic pathways. The Arachidonic acid metabolism pathway, with a most significant p value is the major distinguishing feature of Cluster I from the other two clusters. Additionally, Nicotinate and nicotinamide metabolism pathway and D-Glutamine and D-glutamate metabolism pathway are also differential metabolic pathways that have a remarkable impact on Cluster I compared to the other two clusters.