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. 2024 Jun 19;15:1424815. doi: 10.3389/fphys.2024.1424815

TABLE 1.

Characteristics of included studies.

Study (year) Country Sample size (n) Sex (M/F) Age mean (SD) year K-L grade VR equipment Degree of immersion Duration of rehabilitation Number of treatments Treatment time(min) Outcome
Lin et al. (2020) China EG: 40 EG: 16/24 EG: 55.9 (15.8) ≥2 Hot Plus system Non-immersive 4 weeks 3/week 20 WOMAC, Chronic Pain Scale
CG: 40 CG: 23/17 CG: 58.1 (16.9)
Nambi et al. (2020) Saudi Arabia EG: 20 NA EG: 22.8 (1.3) 2–3 Pro-Kin system Immersive 4 weeks 2/week 20 VAS, WOMAC
CG: 20 CG: 22.6 (1.4)
Mete and Sari (2022) Turkey EG: 30 EG: 6/24 EG: 59.5 (7.0) 2–3 MarVAJED® Immersive 6 weeks 5/week 20 VAS, WOMAC
CG: 30 CG: 7/23 CG: 57.7 (10.9)
Ozlu et al. (2023) Turkey EG: 35 EG: 18/17 EG: 53.28 (10.42) 2–3 the Quest 128 GB type of Oculus brand Immersive 3 weeks 5/week 15 VAS, WOMAC
CG: 38 CG: 12/26 CG: 53.71 (9.65)
Kim et al. (2017) Korea EG: 15 EG: 7/8 EG: 76.5 (8.8) NA Shinhwa, MX-0004SE Non-immersive 8 weeks 3/week 15 Muscle strength
CG: 15 CG: 5/10 CG: 77.7 (7.9)
Lin et al. (2022) China EG: 20 EG: 1/19 EG: 75.6 (4.4) 2 CRE system and LabVIEW software Non-immersive 12 weeks 2/week 30 WOAMC, Muscle strength
CG: 18 CG: 2/16 CG: 76.0 (5.6)
Lin et al. (2007) China EG: 29 EG: 9/20 EG: 61.6 (8.1) ≤3 Acer system Non-immersive 8 weeks 3/week 40 WOMAC, Muscle strength
CG: 26 CG: 5/21 CG: 61.0 (7.7)
Abdelazeem et al. (2016) Saudi Arabia EG: 20 NA EG: 58 (6.0) 2–3 Xbox 360 with Kinetic Sensor Immersive 8 weeks 3/week 15 VAS, WOMAC
CG: 20 CG: 59 (7.0)
Oliveira et al. (2024) Brazilian EG: 20 EG: 6/14 EG: 62.35 (7.39) 2–4 Xbox 360 with Kinetic Sensor Non-immersive 8 weeks 2/week 20 VAS, WOMAC
CG: 20 CG: 3/17 CG: 62.60 (8.62)

EG, experimental group; CG, control group; NA, not available; K-L grade, Kellgren-Lawrence Grade; SD, standard deviation; VAS, visual analogue scale; WOMAC, Western Ontario and McMaster Universities Osteoarthritis Index; 10MWT., 10-m walk test; MMT, manual muscle test.