Figure 3.

Radical‐mediated degradation using a chemical initiator system. 8 µL hydrogels (5 wt.% total polymer content) laden with 1 µm diameter fluorescent polystyrene beads were polymerized in a 96‐well plate, equilibrated in 0.2 m TEMED solution, and treated with an equal volume of either a) 0 m APS (PBS only, final concentration 0.1 m TEMED/0 M APS) or b) 0.2 m APS solution (final concentration 0.1 m TEMED/0.1 m APS). After 15 min, greyscale‐converted fluorescence imaging indicates no change in hydrogel bead localization in the –APS gel while the +APS gel degraded, as indicated by signal dispersion, suggesting bead release. Scale bars = 1 mm. The black line indicates a well boundary. c) Normalized mean grey values inside (solid lines) versus in solution outside (dashed lines) of bead‐laden hydrogels indicate rapid cargo release upon the addition of APS solution (orange) but not PBS only (blue).