TABLE 1.

Information on the research cohort included in this study.

References	DOI	Cohort	Group	CRC+HC (N)	Control (age and gender)	CRC (age and gender)	Disease information	TNM stage (I/II/III/IV)
Jin et al., 2019	10.1111/1462-2920.14498	Harbin	DBHEB	15+31	47 (23–64) (n = 31 21 male + 10 female)	63(54–83) (n = 15 10 male + 5 female)	Carcinoma patients (CRC)	Data not mentioned
Yang et al., 2021	10.1038/s41467-021-27112-y	Shandong	HDSD	54+146	60.46 ± 6.94 (n = 54, 26 male + 28 female)	62.42 ± 7.67 (n = 146 84 male + 62 female)	Sporadic CRC	33/50/57/6
Yi et al., 2021	10.1158/1078-0432.CCR-20-3445	Shanghai	HDSH	84+31	Data not mentioned	55.46 ± 9.47 (n = 84 58 male + 26 female)	Locally advanced rectal cancer	0/9/61/14
Li et al., 2022	10.3389/fcell.2022.916961	Wuxi	HDJS	82+0	No healthy controls	64.77 ± 0.92 (n = 98 58 male + 40 female) Only 82 stool samples included	Patients scheduled for colorectal resection (CRC)	10/51/30/7 (98)
Feng et al., 2023	10.3389/fmicb.2023.1034325	Anhui	HZAH	10+10	54.42 ± 11.40 (n = 10 5 male + 5 female)	57.05 ± 11.58 (n = 10 4 male + 6 female)	Colorectal cancer	0/6/4/0