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. 2024 Jun 10;21(7):3310–3320. doi: 10.1021/acs.molpharmaceut.4c00063

Table 6. Siponimod Solubility in Porcine Vitreous and PBS at Different Time Pointsa.

time (h) siponimod concentration (μg/mL)
  porcine vitreous PBS
24 340.17 ± 82.08 74.64 ± 10.99
48 310.84 ± 90.32 88.31 ± 5.90
72 275.40 ± 6.46 89.34 ± 6.59
96 275.93 ± 14.10 99.50 ± 4.35
a

Values are presented as the average of three independent replicates (n = 3) ± standard deviation.