Table 6. Siponimod Solubility in Porcine Vitreous and PBS at Different Time Pointsa.
time (h) | siponimod concentration (μg/mL) |
|
---|---|---|
porcine vitreous | PBS | |
24 | 340.17 ± 82.08 | 74.64 ± 10.99 |
48 | 310.84 ± 90.32 | 88.31 ± 5.90 |
72 | 275.40 ± 6.46 | 89.34 ± 6.59 |
96 | 275.93 ± 14.10 | 99.50 ± 4.35 |
Values are presented as the average of three independent replicates (n = 3) ± standard deviation.