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TABLE 5.

Thymocyte infection with DH125 dualtropic HIV-1 is partially inhibited by I-309 and SDF-1α but not by MIP-1βa

Chemokine Mean p24 concn (ng/ml) ± SEM % Inhibition
None 79.0 ± 0.78
I-309 64.5 ± 2.3 18
SDF-1α 55.6 ± 0.78 29
I-309 + SDF-1α 61.2 ± 0.78 22
MIP-1β 74.0 ± 3.1 6
a

CD4 SP thymocytes were infected with HIV-1DH125 at an MOI of 0.01. Chemokines were used at 2 μg/ml. Supernatants were harvested on day 10. Chemokine treatment and p24 analyses were performed as described in Table 3, footnote a