Table 4. The final simplified high risk Oncotype DX recurrence score predictive scoring system.
| Variable | Multivariable model | Score* (if applicable) | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p-value | β-coefficient | |||
| Age ≤ 50 | 6.138 | 2.019–18.660 | 0.0014 | 1.8146 | 1 | |
| IDCa tumor type | 3.317 | 0.738–14.914 | 0.0118 | 1.1991 | 1 | |
| Histologic grade 2 or 3 | 7.102 | 1.611–31.309 | 0.0096 | 1.9604 | 1 | |
| Necrosis | 1.684 | 0.615–4.632 | 0.0309 | 0.5232 | 1 | |
| PR negativity | 42.56 | 7.392–245.049 | < 0.0001 | 3.7509 | 1 | |
| Ki-67 LI > 20 | 5.053 | 2.433–10.492 | < 0.0001 | 1.6199 | 1 | |
| Max score | 6 | |||||
OR = odds ratio; CI = confidence interval; IDCa = invasive ductal carcinoma; PR = progesterone receptor; Ki-67 LI = Ki-67 labeling index.
*The item point is 1 if the covariate is valid, otherwise 0. The score is calculated by summing the points associated with each variable that is present.