Table 2.
Clinical, radiological and treatment characteristics of 414 CCMs
| Clinical and radiological data per CCM | n (%) |
| Previous surgery | 21 (5.1%) |
| Location characteristics | |
| Adjacent to the cortex | 253 (61.1%) |
| Adjacent to ependymal plane | 100 (24.2%) |
| Location (anatomic) | |
| Brainstem | 155 (37.4%) |
| Basal ganglia and thalamus | 60 (14.5%) |
| Supratentorial lobar area | 171 (41.3%) |
| Cerebellum | 28 (6.8%) |
| Associated developmental venous anomaly | 50 (12.1%) |
| Number of pre-SRS haemorrhages | |
| 1 | 324 (78.3%) |
| 2 | 71 (17.1%) |
| 3 | 16 (3.9%) |
| 4 | 1 (0.2%) |
| 5 | 2 (0.5%) |
| Median (Q1–Q3) time from diagnosis to SRS, years | 0.9 (0.3–3.1) |
| Zabramski classification | |
| 1 | 78 (19.0%) |
| 2 | 307 (74.7%) |
| 3 | 25 (6.1%) |
| 4 | 1 (0.2%) |
| Unknown | 3 |
| Dosimetric parameter per CCM, median (Q1–Q3) | |
| Target volume, cm3, median (Q1–Q3) | 0.6 (0.2–1.5) |
| Margin dose, Gy, median (Q1–Q3) | 12 (12c14) |
| Isocentres, median (Q1–Q3) | 4 (2–8) |
| Isodose line %, median (Q1–Q3) | 50 (50–51.5) |
CCM, cerebral cavernous malformation; Q1-Q3, first to third quartiles; SRS, stereotactic radiosurgery.