Table 1.
Comparing the baseline characteristics of patients between groups
| Variable | Groups | P-Value | |
|---|---|---|---|
| Vit C (n=105) | Control (n=105) | ||
| Sex | |||
| Male | 52 (49.5) | 66 (62.9) | 0.052 |
| Female | 53 (50.5) | 39 (37.1) | |
| Age (year) | |||
| Median (IQR) | 60 (48 - 67.5) | 65 (51 - 75) | 0.068 |
| Comorbidities | |||
| No | 52 (49.5) | 39 (37.1) | 0.197 |
| Diabetes mellitus | 4 (3.8) | 6 (5.7) | |
| Hypertension | 13 (12.4) | 20 (19) | |
| Hyperlipidemia | 0 (0) | 1 (1) | |
| Ischemic Heart Disease | 4 (3.8) | 2 (1.9) | |
| Immune disorder | 4 (3.8) | 1 (1) | |
| Rheumatoid Arthritis | 1 (1) | 0 (0) | |
| Cancer | 2 (1.9) | 4 (3.8) | |
| Chronic Kidney Disease | 0 (0) | 3 (2.9) | |
| Other* | 25 (23.8) | 29 (27.6) | |
| Past medical history | |||
| Corticosteroid | 5 (4.8) | 3 (2.9) | 0.145 |
| Chemotherapy | 0 (0) | 4 (3.8) | |
| No | 100 (95.2) | 98 (93.3) | |
| APACHE | |||
| Median (IQR) | 14 (10 - 20) | 16 (11 - 23) | 0.055 |
| Duration of hospitalization | |||
| Median (IQR) | 5 (4 - 9) | 5 (3 - 7) | 0.111 |
| Habit | |||
| Smoker | 4 (3.8) | 4 (3.8) | 1.000 |
| Alcohol | 1 (1) | 4 (3.8) | 0.369 |
| Vaccinated | |||
| Yes | 3 (2.9) | 2 (1.9) | 1.000 |
| No | 102 (97.1) | 103 (98.1) | |
| laboratory findings (admission to ICU) | |||
| D-Dimer | 2135 (957.5 - 5387.5) | 1810 (828.5 - 4693.5) | 0.397 |
| CRP | 75 (36.5 - 132) | 95 (47 - 146.5) | 0.025 |
| Lactate dehydrogenase | 870 (534.5 - 1209.5) | 690 (495.5 -1245.5) | 0.280 |
| Ferritin | 663 (455 - 790) | 760 (522.5 - 926) | 0.087 |
| ESR | 40 (20.5 - 55) | 45 (20.25 - 66.5) | 0.347 |
| O2 saturation (%) | |||
| Median (IQR) | 83 (72 - 89.5) | 80 (70 - 89.5) | 0.591 |
| Lung involvement (%) | |||
| Median (IQR) | 70 (50 - 80) | 70 (50 - 80) | 0.418 |
Data are presented as frequency (%) or median (interquartile range (IQR)). *Other diseases in each disease group were so small and rare that they are not listed separately in the table. ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein; ICU: intensive care unit.