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. 2024 May 5;12(1):e46. doi: 10.22037/aaem.v12i1.2284

Table S3.

Evaluation of publication bias using Egger's Test and Trim and Fill method

Egger's Trim and fill method
Subgroup No. of studies in each subgroup intercept p-value Number of trimmed studies Adjusted pooled RR (After trim) p-value
Total (No subgrouping) 42 8.69 0.005 0 1.40 [1.29, 1.52] < 0.001
Temporal lag
≤ 7 14 7.95 0.126 0 1.31 [1.11, 1.55] 0.002
> 7 28 8.96 0.029 14 0.98 [0.79, 1.20] < 0.001
Resolution
Monthly 17 -15.72 0.010 0 1.61 [1.30, 1.92] < 0.001
Weekly 10 4.67 0.022 2 1.06 [0.99, 1.14] < 0.001
Daily 15 2.83 0.652 0 1.32 [1.11, 1.56] < 0.001
Climate group
Subtropical 16 -0.14 0.954 0 1.27 [1.13, 1.43] < 0.001
Tropical 13 19.63 0.043 7 1.05 [0.78, 1.33] < 0.001
Temperate 13 10.09 0.102 0 1.20 [1.11, 1.31] < 0.001
Type of diarrhea
Watery 19 13.90 0.046 9 0.916 [0.76, 1.08] < 0.001
Bacillary dysentery 10 -14.02 0.102 0 1.36 [1.07, 1.74] 0.01
Bacillary dysentery + Watery 8 5.09 0.176 0 1.53 [1.29, 1.81] < 0.001
Dysentery 1 - - - - -
Dysentery + Watery   4 -0.64 0.060 0 1.21 [1.07, 1.36] 0.003
Statistical model
DLNM 7 4.55 0.194 0 1.45 [1.23, 1.70] < 0.001
GAMM 11 -5.64 0.442 0 1.38 [1.22, 1.56] < 0.001
GLM 11 12.94 0.383 0 1.43 [1.14, 1.79] 0.002
GLMM 2 -200.00 - 0 1.03 [1.01, 1.05] 0.002
Other 11 -5.46 0.057 0 1.47 [1.13, 1.91] 0.004
Type of study
Case-control 2 -200.00 - 0 2.29 [2.20, 2.38] < 0.001
Cohort 3 -6.53 0.644 0 2.29 [1.95, 2.69] < 0.001
Cross-sectional 4 13.11 0.029 1 1.10 [0.88, 1.34] < 0.001
Spatial ecology 2 -2.53 - 0 1.03 [1.01, 1.05] 0.002
Time-series 31 5.84 0.011 13 0.95 [0.84, 1.07] < 0.001
HDI level
Medium 10 10.03 0.167 0 1.38 [1.21, 1.57] < 0.001
High 32 1.52 0.721 0 1.39 [1.23, 1.59] < 0.001

HDI: Human Development Index, RR: Relative Risk, CIs: Confidence Intervals, DLNM: Distributed Lag Non-linear Models, GAMM: Generalized Additive Models for Location, Scale, and Shape, GLM: Generalized Linear Models, GLMM: Generalized Linear Mixed Models