Table S3.
Evaluation of publication bias using Egger's Test and Trim and Fill method
| Egger's | Trim and fill method | |||||
|---|---|---|---|---|---|---|
| Subgroup | No. of studies in each subgroup | intercept | p-value | Number of trimmed studies | Adjusted pooled RR (After trim) | p-value |
| Total (No subgrouping) | 42 | 8.69 | 0.005 | 0 | 1.40 [1.29, 1.52] | < 0.001 |
| Temporal lag | ||||||
| ≤ 7 | 14 | 7.95 | 0.126 | 0 | 1.31 [1.11, 1.55] | 0.002 |
| > 7 | 28 | 8.96 | 0.029 | 14 | 0.98 [0.79, 1.20] | < 0.001 |
| Resolution | ||||||
| Monthly | 17 | -15.72 | 0.010 | 0 | 1.61 [1.30, 1.92] | < 0.001 |
| Weekly | 10 | 4.67 | 0.022 | 2 | 1.06 [0.99, 1.14] | < 0.001 |
| Daily | 15 | 2.83 | 0.652 | 0 | 1.32 [1.11, 1.56] | < 0.001 |
| Climate group | ||||||
| Subtropical | 16 | -0.14 | 0.954 | 0 | 1.27 [1.13, 1.43] | < 0.001 |
| Tropical | 13 | 19.63 | 0.043 | 7 | 1.05 [0.78, 1.33] | < 0.001 |
| Temperate | 13 | 10.09 | 0.102 | 0 | 1.20 [1.11, 1.31] | < 0.001 |
| Type of diarrhea | ||||||
| Watery | 19 | 13.90 | 0.046 | 9 | 0.916 [0.76, 1.08] | < 0.001 |
| Bacillary dysentery | 10 | -14.02 | 0.102 | 0 | 1.36 [1.07, 1.74] | 0.01 |
| Bacillary dysentery + Watery | 8 | 5.09 | 0.176 | 0 | 1.53 [1.29, 1.81] | < 0.001 |
| Dysentery | 1 | - | - | - | - | - |
| Dysentery + Watery | 4 | -0.64 0.060 | 0 | 1.21 [1.07, 1.36] | 0.003 | |
| Statistical model | ||||||
| DLNM | 7 | 4.55 | 0.194 | 0 | 1.45 [1.23, 1.70] | < 0.001 |
| GAMM | 11 | -5.64 | 0.442 | 0 | 1.38 [1.22, 1.56] | < 0.001 |
| GLM | 11 | 12.94 | 0.383 | 0 | 1.43 [1.14, 1.79] | 0.002 |
| GLMM | 2 | -200.00 | - | 0 | 1.03 [1.01, 1.05] | 0.002 |
| Other | 11 | -5.46 | 0.057 | 0 | 1.47 [1.13, 1.91] | 0.004 |
| Type of study | ||||||
| Case-control | 2 | -200.00 | - | 0 | 2.29 [2.20, 2.38] | < 0.001 |
| Cohort | 3 | -6.53 | 0.644 | 0 | 2.29 [1.95, 2.69] | < 0.001 |
| Cross-sectional | 4 | 13.11 | 0.029 | 1 | 1.10 [0.88, 1.34] | < 0.001 |
| Spatial ecology | 2 | -2.53 | - | 0 | 1.03 [1.01, 1.05] | 0.002 |
| Time-series | 31 | 5.84 | 0.011 | 13 | 0.95 [0.84, 1.07] | < 0.001 |
| HDI level | ||||||
| Medium | 10 | 10.03 | 0.167 | 0 | 1.38 [1.21, 1.57] | < 0.001 |
| High | 32 | 1.52 | 0.721 | 0 | 1.39 [1.23, 1.59] | < 0.001 |
HDI: Human Development Index, RR: Relative Risk, CIs: Confidence Intervals, DLNM: Distributed Lag Non-linear Models, GAMM: Generalized Additive Models for Location, Scale, and Shape, GLM: Generalized Linear Models, GLMM: Generalized Linear Mixed Models