FIG. 1.

Ly49G2 is expressed on an activated CD8⁺ T-cell population, which expands in response to LCMV infection. C57BL/6 mice (6 to 8 weeks old) were inoculated intraperitoneally with 4 × 10⁴ PFU of LCMV. Splenocytes were harvested from naive or day 8 LCMV-infected mice and examined for Ly49G2 expression on NK cells and CD8 cells (left-hand and central panels, respectively). The percentage of lymphocytes present in the upper two quadrants of each panel is indicated, and the percentage that Ly49G2⁺ cells represent of the NK1.1⁺ and CD8⁺ populations is shown in parentheses. CD8⁺ cells were gated, and the percentage of the Ly49G2⁻ and Ly49G2⁺ fractions coexpressing CD44 is shown (right-hand panels).