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CD8+ Ly49G2+ cells lyse syngeneic LCMV-infected but not H2d allogeneic P815 or YAC-1 targets. Fresh CD8+ Ly49G2− (G2−) and CD8+ Ly49G2+ (G2+) cells, sorted by flow cytometry, were used in CTL assays against LCMV-infected syngeneic (H2b) MC57G and allogeneic (H2d) P815 cells (effector-to-target ratio = 4:1) (A), and the prototypic NK cell target cell line, YAC-1 (effector-to-target ratios = 1.25:1, 2.5:1, and 5:1) (B).
