TABLE 1.
Mx expression in fish vaccinated with IHNV, SHRV, and SVCV G DNA vaccinesa
| Treatment | Challenge dose
|
|||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 103 PFU/ml at dpc:
|
105 PFU/ml at dpc:
|
|||||||||||||||||
| 0
|
1
|
2
|
5
|
7
|
1
|
2
|
5
|
7
|
||||||||||
| K | L | K | L | K | L | K | L | K | L | K | L | K | L | K | L | K | L | |
| IHNV-G | 3/3 | 3/3 | 3/3 | 3/3 | 2/3 | 3/3 | 2/3 | 1/3 | 0/3 | 0/3 | 2/3 | 3/3 | 3/3 | 2/3 | 0/3 | 2/3 | 0/3 | 0/3 |
| SHRV-G | 2/3 | 2/3 | 3/3 | 3/3 | 2/3 | 2/3 | 1/3 | 2/3 | 2/3 | 2/3 | 3/3 | 3/3 | 3/3 | 3/3 | 2/3 | 2/3 | 1/3 | 0/3 |
| SVCV-G | 2/3 | 2/3 | 3/3 | 2/3 | 3/3 | 2/3 | 2/3 | 2/3 | 2/3 | 3/3 | 3/3 | 2/3 | 3/3 | 3/3 | 1/3 | 3/3 | 2/3 | 3/3 |
| pcDNA3 | 0/3 | 0/3 | 0/3 | 0/3 | 0/3 | 0/3 | 2/3 | 1/3 | 3/3 | 3/3 | 0/3 | 0/3 | 2/3 | 1/3 | 2/3 | 3/3 | 3/3 | 3/3 |
| PBS | 0/3 | 0/3 | 0/3 | 0/3 | 1/3 | 1/3 | 2/3 | 2/3 | 3/3 | 3/3 | 0/3 | 0/3 | 0/3 | 0/3 | 3/3 | 3/3 | 2/3 | 2/3 |
a
Mx expression for fish exposed to 103 or 105 PFU of IHNV per ml at 0, 1, 2, 5, and 7 dpc is shown. The ratios denote the number of fish expressing the Mx protein versus the total number of fish examined. K, kidney; L, liver.