Table 3.
Baseline risk factors for the development of atrophy in the foveal central point by 24 months
| Baseline variables | Univariate analysis (logistic regression) | Multiple logistic regression | ||||
|---|---|---|---|---|---|---|
| Odds ratios | 95% CI | p value | Odds ratios | 95% CI | p value | |
| GA lesion size area—inner ring subfield | 1.214 | 0.731–2.018 | 0.454 | – | – | – |
| GA lesion size area—outer ring subfield | 1.140 | 0.773–1.681 | 0.509 | – | – | – |
| Minimum distance from the foveal central circle | 0.999 | 0.996–1.003 | 0.692 | – | – | – |
| Focality (multifocality) | 0.607 | 0.149–2.475 | 0.487 | – | – | – |
| Reticular pseudodrusen | 2.692 | 0.655–11.061 | 0.170 | – | – | – |
| Foveal thin DLS | 0.149 | 0.033–0.681 | 0.014 | 0.138 | 0.027–0.697 | 0.017 |
| Outer retinal layer thickness—foveal central circle | 0.958 | 0.913–1.005 | 0.080 | 0.954 | 0.905–1.007 | 0.087 |
| Outer retinal layer thickness—inner ring subfield | 0.984 | 0.941–1.030 | 0.501 | – | – | – |
| Outer retinal layer thickness—outer ring subfield | 0.985 | 0.937–1.036 | 0.557 | – | – | – |
| RPE to BM volume—foveal central circle | 10,827.045 | 0.000–4.154E + 33 | 0.789 | – | – | – |
CI, confidence interval; GA, geographic atrophy; DLS, double layer sign; RPE, retinal pigment epithelium; BM, Bruch’s membrane