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. 2024 Jun 20;15:1322159. doi: 10.3389/fimmu.2024.1322159

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Copyright © 2024 Lin, Lin, Fan, Zhang, Liang, Han, Liu and Huang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Fibroscopy, radiologic, and histologic features of IgG4-RD patient. (A–C) Fibroscopy and MRI suggest bulging of the right nasopharynx, disappearance of the crypt, and shallow pharyngeal opening of the eustachian tube. Note the involvement of the fatty gap of the right petrostaphylinus. (D) PET-CT showed active FDG metabolism at nasopharynx. (E, F) Hematoxylin-eosin staining demonstrating lymphocytes, plasma cells, and a few neutrophils, eosinophils infiltrate, accompanied by fibrous tissue hyperplasia. Immunohistochemical staining showed IgG4-positive cells, greater than 10/HPF. These images are at a 20X original magnification.