Table 2.
Comparison of pediatric vs. adult patient characteristics.
| Variable | Pediatric (N=35) | Adult (N=167) | p-value |
|---|---|---|---|
| Sex (F:M, F(%)) | 29:6 | 127:40 | 0.515 |
| Age, years | 15.2 ± 3.3 | 36.4 ± 10.4 | <0.001 |
| Tumor size, cm | 2.5 ± 1.4 | 1.6 ± 1.0 | <0.001 |
| Capsule invasion, n (%) | 28 (80.0%) | 127 (76.0%) | 0.777 |
| Multifocality, n (%) | 3 (8.6%) | 18 (10.8%) | 0.583 |
| Bilaterality, n (%) | 16 (45.7%) | 83 (49.7%) | 0.556 |
| Central node, n | |||
| - Total | 11.0 ± 6.6 | 11.1 ± 7.1 | 0.862 |
| - Metastatic | 7.1 ± 5.4 | 7.0 ± 5.7 | 0.813 |
| - Ratio | 0.6 ± 0.3 | 0.6 ± 0.3 | 0.612 |
| Operative extent | 0.085 | ||
| - Lobectomy | 6 (17.1%) | 13 (7.8%) | |
| - Lobectomy with contralateral partial | 2 (5.7%) | 4 (2.4%) | |
| - Total thyroidectomy | 27 (77.1%) | 150 (89.8%) | |
| Neck lymph node dissection | 0.160 | ||
| - None | 1 (2.9%) | 0 (0.0%) | |
| - CCND | 13 (37.1%) | 55 (32.9%) | |
| - MRND + CCND | 21 (60.0%) | 112 (67.1%) | |
| RAI-treated | 26 (74.3%) | 142 (85.0%) | 0.122 |
| T stage | 0.001 | ||
| - T1 | 11(31.4%) | 106 (63.5%) | |
| - T2 | 12 (34.3%) | 23 (13.8%) | |
| - T3 | 8 (22.9%) | 26 (15.6%) | |
| - T4 | 4 (11.4%) | 12 (7.2%) | |
| N stage | 0.686 | ||
| - N0 | 5 (14.3%) | 16 (6.6%) | |
| - N1a | 8 (22.9%) | 40 (24.0%) | |
| - N1b | 22 (62.9%) | 111 (66.5%) | |
| TNM stage 8th | 0.456 | ||
| - Stage I | 35 (100%) | 155 (93.4%) | |
| - Stage II | 0 | 10 (6.0%) | |
| - Stage III | 0 | 2 (1.2%) | |
| - Stage IV | 0 | 0 | |
| No. of recurrences | 8 (22.9%) | 11 (6.6%) | 0.007 |
DSV, diffuse sclerosing variant; CCND, central compartment neck dissection; MRND, modified radical neck dissection; CI, confidence interval; HR, hazard ratio.
CCND, central compartment neck dissection; MRND, modified radical neck dissection.