Table 4.

Subgroup analysis evaluating the prognostic significance of PNI for PFS in GC/GEJC patients treated with ICIs.

Subgroup	NO. of studies	HR (95% CI)	P	Heterogeneity		Model
				I2 (%)	Ph
Country
China	3	0.76 (0.55–1.07)	0.114	80.7	0.006	Random
Japan	2	0.69 (0.45–1.06)	0.088	0	0.578	Fixed
Other	1	0.37 (0.16–0.86)	0.022	–	–	–
Cut-off
≥40	4	0.70 (0.49–0.98)	0.039	80.8	0.001	Random
<40	2	0.70 (0.43–1.13)	0.142	0	0.577	Fixed
Sample size
>100	3	0.76 (0.55–1.06)	0.102	81.7	0.004	Random
<100	3	0.60 (0.39–0.91)	0.016	0	0.377	Fixed
Analysis
Univariate	3	0.95 (0.92–0.97)	<0.001	0	0.389	Fixed
Multivariate	3	0.62 (0.49–0.77)	<0.001	0	0.468	Fixed