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. 2024 Jun 20;15:1352789. doi: 10.3389/fimmu.2024.1352789
(B) Demonstration of associations between genetic variants with sepsis
SNP Total Genotype frequency Model 1 Model 2
WT HET HOM p-value OR 95% CI MAF p-value OR 95% CI
rs17525809 (T253C)
Sepsis 75 68 7 0.001 0.18 (0.06 - 0.52) 0.047 0.001 0.22 (0.08 - 0.59)
Non-sepsis 30 19 11 0.183
rs2230911 (C1096G)
Sepsis 75 62 10 3 0.045 0.107 0.007
Non-sepsis 30 30 0.000
rs3751142 (G1628T)
Sepsis 75 62 10 3 0.045 0.107 0.007
Non-sepsis 30 30 0.000
rs1621388 (G1772A)
Sepsis 75 36 31 8 0.078 0.313 0.021 0.49 (0.26 - 0.90)
Non-sepsis 30 9 13 8 0.483