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. 2024 Jun 12;8(8):bvae114. doi: 10.1210/jendso/bvae114

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© The Author(s) 2024. Published by Oxford University Press on behalf of the Endocrine Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. See the journal About page for additional terms.

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Figure 1. — microRNA sequencing (miRNAseq) identifies differential expression of microRNAs (DE-miRNAs) from urinary exosomes from healthy individuals, patients with type 2 diabetes without nephropathy (T2D − DN), and those with type 2 diabetes with nephropathy (T2D + DN). (A) Principal component analysis of the miRNA expression data from healthy, T2D − DN, and T2D + DN. (B) Heatmap of the differentially expressed miRNA in healthy, T2D − DN, and T2D + DN. The red boxes indicate higher expression and blue boxes indicate the lower expression miRNAs.