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. 2024 May 24;32(2):200818. doi: 10.1016/j.omton.2024.200818

Figure 1.

Figure 1

CNA analysis of PDX mouse models

(A) Study design of PDX generation and CNA profiling. (B) CNA profiles of PDXs across the genome. Copy number losses are shown in blue and copy number gains in red. (C–E) Oncoplots of CNAs in PDX tumors (C) and the TCGA-BLCA (D) and Lindgren et al. (E) cohorts. (F and G) Pearson correlation dot plot of CNA frequency (%) between the PDX and TCGA-BLCA (F) and between the PDX and Lindgren et al. (G) cohorts. (H) Bar graph of CDKN2A CNA frequency (%) in the NMIBC and MIBC of PDX models and the Lindgren et al. and TCGA-BLCA cohorts. Oncoplots were generated by the cBioPortal Oncoprinter tool.