Table 1. Specific Activity of hALAS2 Variants with Saturating PLP.

	no PLP	percent changea	plus PLP (10 μM)	percent changea
WT	11700 ± 1590		11,800 ± 596
V562A	22500 ± 4010	+92%	24,700 ± 3250	+109%
M567I	8170 ± 991	–30%	9660 ± 795	–18%

^aCompared to WT.