Table 1.

Cost comparison of amyloidosis subtyping analysis by laser capture microdissection-liquid chromatography tandem mass spectrometry (LMD/LC–MS/MS) versus MALDI mass spectrometry imaging with ion mobility (MALDI-MSI)

Per sample	LMD/LC-MSMS	MALDI-MSI
Materials ($)	73	32
Sample preparation time hands on (h)	3.5	3
Incubation time (h)	25	18.1
Instrument analysis time (h)	1.3	1.5
Data analysis time (h)	4	4
Total analysis time (h)	33.8	26.6
Total analysis time (days based on 8 h work/day)	4.2	3.3
Cost per sample ($)	624	594