Table 1.
Variable | Group | p value | |
---|---|---|---|
Liberal (21) | Restrictive (23) | ||
Tomographic follow-up according to the allocated group | |||
Post-randomization head CT | 19/21 (90) | 19/23 (83) | 0.66 |
Post-randomization PHI | 1 (5) | 3 (16) | 0.35 |
Post-randomization ischemia | 4 (21) | 3 (16) | > 0.9 |
Worsening of previous ischemia | 1/4 (25) | 3/3 (100) | 0.14 |
New ischemia | 3/4 (75) | 2/3 (67) | > 0.9 |
Extensive ischemia | 0/4 (0.0) | 3/3 (100) | 0.02 |
Pre-randomization ischemia | 9 (43) | 16 (70) | 0.12 |
Vasospasm prevalence | 4 (19) | 15 (65) | < 0.01 |
Lindegaard ratio (among patients with vasospasm) | 4.2 ± 0.8 | 4.4 ± 1.2 | 0.09 |
MCA blood velocities (cm/s) | Pre-rand. 112.4 ± 21.6 | Pre-rand. 109.8 ± 15.9 | < 0.02 |
Post-rand. 71.4 ± 18.2 | Post-rand. 101.2 ± 16.7 | ||
Tomographic follow-up according to tSAH | |||
Post-rand. new or ischemic zone enlargement n = 7 | Pre-rand. tSAH 6 (85) | No pre-rand. tSAH 1 (14) | 0.01 |
Data presented as n (%). CT, computed tomography; PHI, progressive hemorrhagic injury; TCD, transcranial Doppler; tSAH, traumatic subarachnoid hemorrhage