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. 2024 Jul 3;28:218. doi: 10.1186/s13054-024-04981-5

Table 1.

Main results

Variable Group p value
Liberal (21) Restrictive (23)
Tomographic follow-up according to the allocated group
Post-randomization head CT 19/21 (90) 19/23 (83) 0.66
Post-randomization PHI 1 (5) 3 (16) 0.35
Post-randomization ischemia 4 (21) 3 (16)  > 0.9
Worsening of previous ischemia 1/4 (25) 3/3 (100) 0.14
New ischemia 3/4 (75) 2/3 (67)  > 0.9
Extensive ischemia 0/4 (0.0) 3/3 (100) 0.02
Pre-randomization ischemia 9 (43) 16 (70) 0.12
Vasospasm prevalence 4 (19) 15 (65)  < 0.01
Lindegaard ratio (among patients with vasospasm) 4.2 ± 0.8 4.4 ± 1.2 0.09
MCA blood velocities (cm/s) Pre-rand. 112.4 ± 21.6 Pre-rand. 109.8 ± 15.9  < 0.02
Post-rand. 71.4 ± 18.2 Post-rand. 101.2 ± 16.7
Tomographic follow-up according to tSAH
Post-rand. new or ischemic zone enlargement n = 7 Pre-rand. tSAH 6 (85) No pre-rand. tSAH 1 (14) 0.01

Data presented as n (%). CT, computed tomography; PHI, progressive hemorrhagic injury; TCD, transcranial Doppler; tSAH, traumatic subarachnoid hemorrhage