Table 1:
Characteristics of participants at visit 2 and visit 5 in the Atherosclerosis Risk in Communities Neurocognitive Study
| Characteristics | Midlife (Visit 2) characteristics in the analytic sample for cross-temporal analysis, n=1787 | Later-life (Visit 5) characteristics in the analytic sample for cross-sectional analysis, n=1223 |
|---|---|---|
| FEV1 (L), mean (SD) | 2.83 (0.69) | 2.09 (0.62) |
| FVC (L), mean (SD) | 3.75 (0.91) | 2.91 (0.86) |
| FEV1/FVC%, mean (SD) | 75.75 (6.41) | 72.34 (9.16) |
| Lung function category, n (%) | ||
| Normal | 1480 (83%) | 965 (79%) |
| Restrictive lung condition | 56 (3%) | 78 (6%) |
| Obstructive lung condition | 251 (14%) | 180 (15%) |
| Age (years), mean (SD) | 55.64 (5.22) | 75.93 (5.25) |
| Male sex, n (%) | 722 (40%) | 481 (39%) |
| Smoking status, n (%) | ||
| Never | 845 (47%) | 537 (44%) |
| Former | 670 (37%) | 630 (52%) |
| Current | 272 (15%) | 56 (5%) |
| Black race, n (%) | 495 (28%) | 347 (28%) |
| Center, n (%) | ||
| Forsyth, NC | 453 (25%) | 273 (22%) |
| Jackson, MS | 462 (26%) | 329 (27%) |
| Minneapolis, MN | 418 (23%) | 281 (23%) |
| Washington, MD | 454 (25%) | 340 (28%) |
| Education, n (%) | ||
| < High school | 242 (14%) | 152 (12%) |
| High school | 732 (41%) | 493 (40%) |
| > High school | 813 (45%) | 578 (47%) |
| BMI (kg/m2), mean (SD) | 27.42 (5.02) | 28.38 (5.54) |
| Weight (kg), mean (SD) | 80.37 (17.57) | 77.67 (16.08) |
| Height (m), mean (SD) | 1.68 (0.09) | 1.68 (0.09) |
| Physical activity index, mean (SD) | 2.41 (0.56) | 2.27 (0.64) |
| Coronary heart disease, n (%) | 26 (1%) | 103 (8%) |
| Diabetes, n (%) | 105 (6%) | 392 (32%) |
| Blood Pressure, n (%) | ||
| Normal | 980 (55%) | 152 (12%) |
| Prehypertension | 362 (20%) | 171 (14%) |
| Hypertension | 445 (25%) | 900 (74%) |
| Total cholesterol (mmol/L) | 5.38 (0.95) | 4.76 (1.09) |
| APOE ε4 status (≥1 ε4 allele)(n (%) | 526 (29%) | 351 (29%) |
| Cognition status, n (%) | ||
| Normal | 1787 (100%) | 816 (67%) |
| Mild cognitive impairment | - | 406 (33%) |
Note: BMI, Body Mass Index; FEV1, Forced Expiratory Volume in one second; FVC, Forced Vital Capacity; SD, Standard Deviation.
Information on sex, race, education, center, and APOE ε4 carrier status was obtained from ARIC visit 1. Other than for these characteristics, we present descriptive statistics for visit 2 and visit 5 characteristics. All participants were cognitively normal at visit 2 exam.
Table 1 presents the unweighted characteristics.