Table 2. Box–Behnken Factorial Design with the Independent Variables and Experimental and Predicted TPC Values in Aqueous Olive Tree L. Extracta.
| run | coded
variable |
actual variable |
TPC [μg GAE/mL] |
||||||
|---|---|---|---|---|---|---|---|---|---|
| x1 [g/mL] | x2 [°C] | x3 [min] | X1 [g/mL] | X2 [°C] | X3 [min] | actual | predicted | residual | |
| 1 | –1 | –1 | 0 | 0.008 | 50 | 70 | 97.13 | 94.96 | 2.17 |
| 2 | 1 | –1 | 0 | 0.016 | 50 | 70 | 121.47 | 121.67 | –0.20 |
| 3 | –1 | 1 | 0 | 0.008 | 90 | 70 | 133.47 | 133.27 | 0.20 |
| 4 | 1 | 1 | 0 | 0.016 | 90 | 70 | 156.00 | 158.17 | 0.10 |
| 5 | –1 | 0 | –1 | 0.008 | 70 | 50 | 109.13 | 108.89 | 0.12 |
| 6 | 1 | 0 | –1 | 0.016 | 70 | 50 | 139.80 | 137.20 | –2,17 |
| 7 | –1 | 0 | 1 | 0.008 | 70 | 90 | 126.23 | 128.84 | –2.61 |
| 8 | 1 | 0 | 1 | 0.016 | 70 | 90 | 151.90 | 152.14 | –0.24 |
| 9 | 0 | –1 | –1 | 0.012 | 50 | 50 | 93.23 | 95.64 | –2,41 |
| 10 | 0 | 1 | –1 | 0.012 | 90 | 50 | 134.23 | 134.66 | –0.43 |
| 11 | 0 | –1 | 1 | 0.012 | 50 | 90 | 115.13 | 114.70 | 0.43 |
| 12 | 0 | 1 | 1 | 0.012 | 90 | 90 | 152.90 | 150.49 | 2.41 |
| 13 | 0 | 0 | 0 | 0.012 | 70 | 70 | 143.90 | 143.30 | 0.30 |
| 14 | 0 | 0 | 0 | 0.012 | 70 | 70 | 144.13 | 143.30 | 0.83 |
| 15 | 0 | 0 | 0 | 0.012 | 70 | 70 | 143.33 | 143.30 | 0.03 |
| 16 | 0 | 0 | 0 | 0.012 | 70 | 70 | 142.67 | 143.30 | –0.63 |
| 17 | 0 | 0 | 0 | 0.012 | 70 | 70 | 142.47 | 143.30 | –0.83 |
Note: x1 and X1—biomass weight/extraction solvent ratio, x2 and X2—extraction temperature [°C], and x3 and X3—extraction time [min].