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The 2 × 2 Table for the Comparison of a Binary Outcome From Ophthalmic Studies Using a Paired Design With N Subjects
| Outcome in the Contralateral Eye Assigned to Treatment B | ||||
|---|---|---|---|---|
| Outcome in the Eye Assigned to Treatment A | No | Yes | Total | Anticipated Proportions |
| No | a | b | a + b | 1 − πA |
| Yes | c | d | c + d | πA |
| Total | a + c | b + d | N = a + b + c + d | |
| Anticipated proportions | 1 − πB | πB | ||
