Table 2.
Multivariate regression analysis with quality of life as dependent variable.
| Model R2 = 35%, F = 6.33, p < 0.01 | QoL | |
|---|---|---|
| Predictor | Coeff. | Std. error, CI |
| (Intercept) | 55.64*** | (12.84, CI = [30.33, 80.96]) |
| Age | 0.16 | (0.11, CI = [−0.06, 0.39]) |
| Karnofsky | −0.01 | (0.04, CI = [−0.09, 0.07]) |
| Education | −0.25 | (1.15, CI = [−2.52, 2.02]) |
| Gender (female) | 1.43 | (2.81, CI = [−4.11, 6.97]) |
| Disease stage (metastatic) | −2.94 | (2.67, CI = [−8.21, 2.33]) |
| C30 Fatigue | −0.29** | (0.09, CI = [−0.47, −0.12]) |
| C30 Nausea | 0.13* | (0.07, CI = [0.00, 0.26]) |
| C30 Pain | −0.09 | (0.07, CI = [−0.22, 0.05]) |
| C30 Dyspnea | −0.07 | (0.06, CI = [−0.18, 0.05]) |
| C30 Insomnia | −0.00 | (0.05, CI = [−0.10, 0.10]) |
| C30 Loss of appetite | −0.12* | (0.06, CI = [−0.24, −0.01]) |
| C30 Constipation | 0.00 | (0.05, CI = [−0.09, 0.10]) |
| C30 Diarrhea | −0.21*** | (0.06, CI = [−0.33, −0.09]) |
| Mini MAC Fighting | 0.90 | (0.59, CI = [−0.27, 2.07]) |
| Mini MAC Hopelessness | 0.24 | (0.32, CI = [−0.40, 0.88]) |
| Mini MAC Anxious preoccupation | −0.41 | (0.35, CI = [−1.09, 0.28]) |
| Mini MAC Fatalism | 0.32 | (0.60, CI = [−0.86, 1.51]) |
| Mini MAC Avoidant | −0.11 | (0.41, CI = [−0.93, 0.71]) |
| Perceived severity (reverse) | 1.50* | (0.71, CI = [0.10, 2.91]) |
| Perceived curability | −0.24 | (0.78, CI = [−1.78, 1.29]) |
| DT | −0.82 | (0.51, CI = [−1.83, 0.20]) |
| INFO 25 Information on treatment | 0.02 | (0.06, CI = [−0.11, 0.14]) |
Multivariate regression analysis with quality of life as dependent variable and sociodemographic variables, performance status (Karnofsky), somatic symptoms (EORTC QLQ C-30), coping styles (Mini-MAC) and perception of curability and severity of the disease as predictors. ***p < 0.001; **p < 0.01; *p < 0.05.