. Author manuscript; available in PMC: 2024 Jul 5.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Dec 9;1869(2):159446. doi: 10.1016/j.bbalip.2023.159446

Table 1.

Body weight and composition for mice with WD at 16 weeks of age.

n (F/M)	C3H	tx-j	FC	p-Value	WT	Atp7b^−/− B6	FC	p-Value
n (F/M)	12 (6/6)	18 (10/8)	FC	p-Value	25 (13/12)	23 (11/12)	FC	p-Value

BWt (g)	31.30 ± 2.19	24.70 ± 2.28	0.79	1.70E-07	26.40 ± 3.27	25.40 ± 2.78	0.96	0.364
LWt (g)	1.68 ± 0.15	1.41 ± 0.07	0.84	5.20E-08	1.20 ± 0.36	1.38 ± 0.20	1.15	0.0511
MWAT (g)	0.275 ± 0.100	0.133 ± 0.039	0.484	2.0E-06	0.113 ± 0.057	0.091 ± 0.023	0.805	0.161
LWt:BWt	0.054 ± 0.003	0.057 ± 0.004	1.070	0.00964	0.045 ± 0.011	0.054 ± 0.008	1.200	0.00032
LCu^* (μg/g)	4.84 ± 0.17	260.1 ± 8.78	53.70	3.2E-10	7.42 ± 1.25	194.8 ± 12.35	26.26	5.14E-11

Data are presented as mean ± SEM (nominal data). Comparisons were performed by t-test.

n (F/M) for liver copper: C3H 10 (5/5), tx-j 10 (5/5), WT 17 (12/5), KO 17 (11/6).

Atp7b^−/−, Atp7b global knockout on a C57Bl/6 background; BWt, Body weight; C3H, C3HeB/FeJ control for tx-j; FC, Fold change; LCu, Liver copper; LWt, Liver weight; MWAT, Mesenteric white adipose tissue; tx-j, The Jackson Laboratory toxic milk mouse; WT, Atp7b^+/+ wild type control for Atp7b^−/−.