. Author manuscript; available in PMC: 2024 Jul 5.

Published in final edited form as: Biochim Biophys Acta Mol Cell Biol Lipids. 2023 Dec 9;1869(2):159446. doi: 10.1016/j.bbalip.2023.159446

Table 2.

Liver histological characteristics for mice with WD at 16 weeks of age.

n (F/M)		C3H	tx-j	p-Value	WT	Atp7b^−/−B6	p-Value
		12 (6/6)	18 (10/8)		25 (13/12)	23 (11/12)

	0 foci	8 (67)	1 (6)	0.0005	8 (32)	0 (0)	0.0033
Inflammation	1–2 foci	3 (25)	9 (50)	0.178	12 (48)	5 (22)	0.0628
Inflammation	3–4 foci	1 (8)	7 (38)	0.0712	4 (16)	2 (9)	0.471
	>4 foci	0 (0)	1 (6)	0.733	1 (4)	16 (69)	0.0001

Data are presented as percent (categorical data). Comparisons were performed by chi-square test (categorical).

Atp7b^−/−B6, Atp7b global knockout on a C57Bl/6 background; C3H, C3HeB/FeJ control for tx-j; tx-j, The Jackson Laboratory toxic milk mouse; WT, Atp7b^+/+ wild type control for Atp7b^−/− B6.