Table 2.
Descriptive statistics of kynurenine, kynurenine downstream metabolites, and their ratios at admission (t1).
| Non-Responder M (SD) |
Responder M (SD) |
Statistics | |
|---|---|---|---|
| KYN [ng/ml] | 423.81 (103.34) | 445.91 (119.33) | T(81) = -0.87, p = .378 |
| 3-HK [ng/ml] | 17.02 (5.35) | 15.62 (4.67) | T(81) = 1.28, p = .206 |
| 3-HAA [ng/ml] | 9.45 (3.22) | 7.93 (1.81) | T(44.4) = 2.41*, p = .010 |
| QA [ng/ml] | 64.14 (21.39) | 66.13 (32.08) | T(81) = -0.32, p = .218 |
| NA [ng/ml] | 16.25 (8.22) | 13.30 (8.41) | T(80) = 1.58, p = .116 |
| KYNA [ng/ml] | 7.88 (3.02) | 8.20 (2.97) | T(81) = -0.49, p = .624 |
| AA [ng/ml] | 2.43 (1.00) | 2.31 (0.68) | T(51.48) = 0.57, p = .569 |
| XA [ng/ml] | 2.61 (1.98) | 2.37 (1.17) | T(79) = 0.69, p = .501 |
| PA [ng/ml] | 19.54 (10.27) | 20.43 (11.98) | T(81) = -0.36, p = .723 |
| 3-HK/KYN | 0.041 (0.01) | 0.036 (0.01) | T(81) = 2.38**, p = .020 |
| 3-HAA/KYN | 0.0190 (0.01) | 0.0189 (0.01) | T(77) = 2.06*, p = .043 |
| KYNA/KYN | 0.0190 (0.01) | 0.0189 (0.01) | T(81) = -0.06, p = .950 |
| 3-HK/KYNA | 2.32 (0.78) | 2.04 (0.68) | T(81) = 1.75, p = .084 |
| KYNA/QA | 0.13 (0.05) | 0.14 (0.09) | T(81) = -0.80, p = .285 |
| AA/KYN | 0.34 (0.20) | 0.31 (0.14) | T(72) = 0.86, p = .395 |
KYN, Kynurenine; XA, Xanthurenic Acid; KYNA, Kynurenic acid; 3-HAA, 3-Hydroxyanthranilic acid; NA, Nicotinic acid; PA, Picolinic acid; QA, Quinolinic acid; AA, Anthralinic acid; 3-HK, 3-Hydroxykynurenine; 3-HK/KYN ratio, 3-Hydroxykynurenine/kynurenine; 3-HAA/ KYN ratio, 3-Hydroxyanthranilic acid/kynurenine; KYNA/ KYN ratio, Kynurenic acid/kynurenine; 3-HK/KYNA ratio, 3-Hydroxykynurenine/kynurenic acid; KYNA/QA ratio, Kynurenine/quinolinic acid; AA/KYN, Anthralinic acid/kynurenine. Significant results are printed in bold. *p < .05, **p < .01.