Table 3.
Descriptive statistics of kynurenine, kynurenine downstream metabolites, and their ratios at discharge (t2).
| Non-Responder M (SD) |
Responder M (SD) |
Statistics | |
|---|---|---|---|
| KYN [ng/ml] | 458.92 (125.67) | 430.94 (95.63) | T(82) = 1.16, p = .250 |
| 3-HK [ng/ml] | 16.86 (5.04) | 15.83 (6.65) | T(82) = 0.79, p = .435 |
| 3-HAA [ng/ml] | 10.35 (4.10) | 8.01 (2.34) | T(46.97) = 2.99**, p = .004 |
| QA [ng/ml] | 63.95 (20.99) | 58.72 (18.01) | T(82) = 1.23, p = .224 |
| NA [ng/ml] | 14.36 (9.92) | 10.16 (8.98) | T(79) = 1.99, p = .050 |
| KYNA [ng/ml] | 7.93 (2.74) | 7.92 (2.60) | T(82) = 0.10, p = .992 |
| AA [ng/ml] | 2.61 (1.22) | 2.01 (0.52) | T(39.51) = 2.61**, p = .013 |
| XA [ng/ml] | 2.81 (2.07) | 2.19 (1.20) | T(81) = 0.87, p = .387 |
| PA [ng/ml] | 19.74 (8.52) | 20.13 (10.78) | T(82) = -0.18, p = .855 |
| 3-HK/KYN | 0.0374 (0.01) | 0.0370 (0.01) | T(82) = 0.15, p = .878 |
| 3-HAA/KYN | 0.023 (0.01) | 0.019 (0.01) | T(77) = 1.85, p = .069 |
| KYNA/KYN | 0.0176 (0.01) | 0.0186 (0.01) | T(82) = -0.91, p = .368 |
| 3-HK/KYNA | 2.22 (0.58) | 2.19 (1.39) | T(82) = 0.12, p = .902 |
| KYNA/QA | 0.14 (0.05) | 0.14 (0.07) | T(82) = -1.07, p = .286 |
| AA/KYN | 0.35 (0.16) | 0.28 (0.11) | T(52.49) = 2.08*, p = .043 |
KYN, Kynurenine; XA, Xanthurenic Acid; KYNA, Kynurenic acid; 3-HAA, 3-Hydroxyanthranilic acid; NA, Nicotinic acid; PA, Picolinic acid; QA, Quinolinic acid; AA, Anthralinic acid; 3-HK, 3-Hydroxykynurenine; 3-HK/KYN ratio, 3-Hydroxykynurenine/kynurenine; 3-HAA/ KYN ratio, 3-Hydroxyanthranilic acid/kynurenine; KYNA/ KYN ratio, Kynurenic acid/kynurenine; 3-HK/KYNA ratio, 3-Hydroxykynurenine/kynurenic acid; KYNA/QA ratio, Kynurenine/quinolinic acid; AA/KYN, Anthralinic acid/kynurenine. Significant results are printed in bold. *p < .05, **p < .01.