TABLE 1.
Baseline Characteristics by Treatment Arm*
| n/N (%) | ||
|---|---|---|
| Characteristics | Standard care (N=98) | Cold stored platelets (N=102) |
| Age [mean (SD)] | 35.3 (14.4) | 34.4 (13.5) |
| Male sex | 78/98 (80) | 85/102 (83) |
| Race | ||
| White | 18/98 (18) | 28/102 (28) |
| Black | 51/98 (52) | 47/102 (47) |
| Other | 13/98 (13) | 13/102 (13) |
| Hispanic | 13/98 (13) | 20/102 (20) |
| SBP [median (IQR)] (mm Hg) | ||
| Initial | 108.5 (84.5, 129.5) | 99 (83, 140) |
| Highest | 122 (102, 144) | 127 (98, 148) |
| Lowest | 93.5 (78, 117.5) | 90 (78, 127) |
| HR [median (IQR)] (beats/min) | ||
| Initial | 106 (86, 123) | 112 (88, 130.5) |
| Highest | 111.5 (93, 130) | 116 (96.5, 135) |
| Lowest | 95 (81.5, 117) | 101 (75, 123) |
| Transport mode | ||
| Ground EMS | 66/98 (67) | 71/102 (70) |
| Air EMS | 24/98 (24) | 20/102 (20) |
| Does not apply† | 5/98 (5) | 4/102 (4) |
| Transferred from | ||
| Scene of accident/injury | 65/98 (66) | 73/102 (72) |
| Home | 4/98 (4) | 3/102 (3) |
| Other hospital | 26/98 (26) | 19/102 (19) |
| Mechanism of injury blunt | 23/98 (23) | 12/102 (12) |
| Fall | 5/98 (5) | 2/102 (2) |
| MVC occupant ejected | 3/98 (3) | 1/102 (1) |
| MVC occupant not ejected | 6/98 (6) | 3/102 (3) |
| MVC motorcycle | 5/98 (5) | 3/102 (3) |
| MVCpedestrian | 1/98 (1) | 2/102 (2) |
| Struck by or against | 3/98 (3) | 1/102 (1) |
| Mechanism of injury penetrating | 76/98 (77) | 90/102 (88) |
| Firearm | 53/98 (54) | 62 /102 (61) |
| Impalement | 1/98 (1) | 1/102 (1) |
| Stabbing | 20/98 (20) | 26/102 (25) |
| Other | 2/98 (2) | 1/102 (1) |
| AIS [median (IQR)] | ||
| Head and Neck AIS | 0, (0, 0) | 0, (0, 0) |
| Face AIS | 0, (0, 0) | 0, (0, 0) |
| Chest AIS | 1.5 (0, 3) | 0 (0, 3) |
| Abdomen AIS | 3 (0, 4) | 2 (0, 4) |
| External AIS | 1 (0, 1) | 1 (0, 1) |
| Extremity AIS | 0 (0, 3) | 0 (0, 3) |
| ISS‡ [median (IQR)] | 17.5 (10, 29) | 17 (9, 27) |
| TBI | 9/98 (9) | 6/102 (6) |
| Prehospital advanced airway§ | 16/98 (16) | 12/102 (12) |
| Supraglottic airway | 2/98 (2) | 1/102 (1) |
| Endotracheal intubation | 14/98 (14) | 11/102 (11) |
| Prehospital crystalloid/colloid fluids§ | 42/98 (43) | 36/102 (35) |
| Crystalloid/colloid volume [median (IQR)] (mL) | 1000 (300, 1000) | 700 (300, 2000) |
| Prehospital blood product§ | ||
| Whole blood | 6/98 (6) | 6/102 (6) |
| Whole blood volume [median (IQR)] (U) | 1 (1, 1) | 1.5 (1, 2) |
| Plasma | 14/98 (14) | 9/102 (9) |
| Plasma volume [median (IQR)] (U) | 2 (1, 2) | 2 (2, 2) |
| Red blood cell | 22/98 (22) | 14/102 (14) |
| Red blood cell volume [median (IQR)] (U) | 2 (1, 3) | 2 (1, 4) |
| Platelets | 1/98 (1) | 0/102 (0) |
AIS indicates Abbreviated Injury Score; ED, emergency department; EMS, Emergency Medical Services; HR, heart rate; IQR, interquartile range; ISS, Injury Severity Score; MVC, motor vehicle crash; RR, respiratory rate; SBP, systolic blood pressure; TBI, traumatic brain injury.
*
No statistically significant differences were observed between baseline characteristics.
†
Not delivered to the ED by EMS.
‡
The score range was 0 to 75. A score >15 indicates major trauma.
§
Provided by EMS during transport or at an outside ED before transfer.