Table 2. Univariate analysis of potential variables associated with overall survival.
Variable | Hazard radio | 95% confidence interval | Log-rank P-value | |
---|---|---|---|---|
Age (≥66 vs. <66 years) | 0.76 | 0.36–1.61 | 0.477 | |
Sex (male vs. female) | 0.92 | 0.39–2.16 | 0.840 | |
Siewert classification | 0.757 | |||
II vs. I | 1.43 | 0.56–3.69 | ||
III vs. I | 1.19 | 0.45–3.15 | ||
III vs. II | 0.83 | 0.33–2.10 | ||
Clinical stage (III/IV vs. II) | 1.09 | 0.33–3.60 | 0.377 | |
Chemoradiation (yes vs. no) | 0.68 | 030–1.53 | 0.355 | |
Chemotherapy (yes vs. no) | 1.46 | 0.69–3.10 | 0.322 | |
D2 LN dissection (yes vs. no) | 1.26 | 0.57–2.78 | 0.564 | |
Surgical approach (EG vs. TG) | 0.94 | 0.36–2.50 | 0.917 | |
LN involvement (present vs. absent) | 3.89 | 1.68–9.01 | 0.007 | |
Pathologic stage (III/IV vs. I/II) | 4.92 | 2.20–11.04 | <0.001 | |
Pathologic grade (poorly differentiated vs. moderately differentiated) | 1.08 | 0.71–1.63 | 0.740 | |
Histologic type (diffuse vs. intestinal) | 2.33 | 1.10–4.90 | 0.021 | |
Tumor regression score (partial/poor vs. near complete/complete) | 3.15 | 1.32–7.54 | 0.012 | |
Recurrence (yes vs. no) | 3.19 | 1.35–7.53 | 0.005 |
Bold styled values indicate statistically significant.
LN = lymph node; EG = esophagogastrectomy; TG = total gastrectomy.