Table 3. Perioperative factors, pathologic data and recurrence outcomes by histologic type.
Variable | Intestinal (n=36) | Diffuse (n=20) | P-value | |
---|---|---|---|---|
D2 LN dissection performed | 15 (41.7) | 6 (30) | 0.390 | |
Pathologic lymph nodes | ||||
Positive status | 16 (44.4) | 14 (70) | 0.066 | |
Total number harvested | 31 [14–47] | 28 [17–51] | 0.549 | |
Total number positive | 1 (0–12) | 3 (0–17) | 0.058 | |
Positive surgical margin | 1 (2.8) | 2 (10) | 0.250 | |
Pathologic stage | 0.008 | |||
I/II | 24 (66.7) | 6 (30) | ||
III/IV | 12 (33.3) | 14 (70) | ||
Pathologic grade† | 0.004 | |||
Moderately differentiated* | 15 (41.7) | 1 (5.0) | ||
Poorly differentiated | 20 (55.6) | 18 (90.0) | ||
Tumor regression score‡ | 0.910 | |||
Complete response | 8 (22.2) | 3 (15.0) | ||
Near complete response | 7 (19.4) | 4 (20.0) | ||
Partial response | 15 (41.7) | 10 (50.0) | ||
Poor or no response | 5 (13.9) | 3 (15.0) | ||
Recurrence | ||||
All | 15 (41.7) | 14 (70.0) | 0.042 | |
Intrathoracic | 8 (22.2) | 6 (30.0) | 0.520 | |
Intraabdominal | 8 (22.2) | 12 (60.0) | 0.005 | |
Lymph nodes | 5 (13.9) | 8 (40.0) | 0.027 | |
Peritoneum | 4 (11.1) | 6 (30.0) | 0.077 | |
Liver | 1 (2.8) | 4 (20.0) | 0.030 | |
Local | 3 (8.3) | 0 (0.0) | 0.184 | |
Bone | 1 (2.8) | 3 (15.0) | 0.089 | |
Brain | 1 (2.8) | 1 (5.0) | 0.668 |
Values are presented as number (%), median (range), or median [interquartile range]. Bold styled P-values indicate statistically significant.
LN = lymph node.
*Includes one patient with well-differentiated pathologic grade.
†One patient in each group (diffuse and intestinal) missing pathologic grade data.
‡One patient in the intestinal group is missing tumor regression score data.