Table 2.
Summary of study outcomes, measurement occasions, and validated tools
| Measures | Format | Administration Timing | Tools |
|---|---|---|---|
| Primary Outcomes | |||
| Cognitive function | In lab | Baseline, 12,18,24 weeks | MoCA, CERAD |
| Mobile | Baseline, 19, 25 weeks (4 days each) | M2C2 Mobile application | |
| Weeks 12 and 13 (14 days) | |||
| Secondary Outcomes | |||
| Quality of life | In lab | Baseline, 12,18,24 weeks | EQ-5D-5 L |
| Physical activity | In lab | Baseline, 12,18,24 weeks | CHAMPS |
| Mobile | Weeks 12 and 13 (14 days) | ActivPAL accelerometer | |
| Mindfulness | In lab | Baseline, 12,18,24 weeks | FFMQ, MAAS |
| Overall health status | In lab | Baseline, 12,18,24 weeks | SF-36 |
| Mobility and gait speed | In lab | Baseline, 12,18,24 weeks | 10-meter walk test |
| Perceived stress | In lab | Baseline, 12,18,24 weeks | PSS-10 |
| Depressive symptoms | In lab | Baseline, 12,18,24 weeks | CES-D |
| Sleep quality | In lab | Baseline, 12,18,24 weeks | PSQI |
| Other Covariates | |||
| Demographics | In lab | Baseline | Survey questions |
| Height and weight | In lab | Baseline | PhenX Toolkit |
| Body Mass Index (BMI) | In lab | Baseline | Calculated (= kg/m2) |
| Waist circumference | In lab | Baseline | PhenX Toolkit |
| Blood pressure | In lab | Baseline | PhenX Toolkit |
| Health literacy | In lab | Baseline | Validated survey item |
| Grip strength | In lab | Baseline | PhenX Toolkit |
| Daily functioning | In lab | Baseline | IADL |
| Social support | In lab | Baseline | PSSS |
| Medication use | In lab | Baseline | Survey questions |
Note: MoCA: Montreal Cognitive Assessment; CERAD: Consortium to Establish a Registry for Alzheimer’s Disease subjective cognitive decline scale; M2C2: Mobile Monitoring of Cognitive Change app; EQ-5D-5L: EuroQol 5 dimensions and 5 levels of response quality of life survey; CHAMPS: Community Health Activities Model Program for Seniors physical activity questionnaire; FFMQ: Five Facet Mindfulness Questionnaire; MAAS: Mindfulness Attention Awareness Scale; SF-36: 36-Item Short Form Health Survey; PSS-10: 10-item Perceived Stress Scale; CES-D: Center for Epidemiological Studies-Depression Scale; PSQI: Pittsburgh Sleep Quality Index; IADL: Instrumental Activities of Daily Living Scale; PSSS: Perceived Social Support Scale