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. 2024 Jul 4;23:232. doi: 10.1186/s12933-024-02343-7

Table 4.

HRs of TyG-related indices for all-cause and cause-specific mortality among participants with MASLD.

Model 1 Model 2
HR (95% CI) p value HR (95% CI) p value
Outcome: All-cause deaths
TyG index 1.182 (1.106, 1.263) <0.001 1.068 (0.984, 1.160) 0.117
TyG-BMI index 1.002 (1.001, 1.003) <0.001 1.002 (1.001, 1.003) <0.001
TyG-WC index 1.001 (1.001,1.002) <0.001 1.001 (1.000,1.002) <0.001
Outcome: Cardiovascular specific deaths
TyG index 1.055 (0.940, 1.220) 0.310 1.059 (0.897, 1.250) 0.500
TyG-BMI index 1.003 (1.001, 1.004) 0.002 1.002 (1.001,1.004) 0.005
TyG-WC index 1.001 (1.000, 1.002) 0.002 1.001 (1.000, 1.002) 0.005
Outcome: Diabetes-specific deaths
TyG index 1.840 (1.476, 2.290) <0.001 1.077 (0.810, 1.432) 0.610
TyG-BMI index 1.009 (1.006, 1.010) <0.001 1.004 (1.001, 1.010) 0.013
TyG-WC index 1.004 (1.003, 1.008) <0.001 1.002 (1.001, 1.003) 0.021

Survey weight-adjusted multivariable Cox proportional hazard models were performed for all-causes mortality. Competing risk analyses of cause-specific mortality were performed. Model 1 was adjusted for baseline age, sex, and race/ethnicity. Model 2 was further adjusted for income, marital status, education, smoking, sedentary lifestyle, diabetes, hypertension, plasma HDL-C, and FIB-4 in addition to model 1

BMI, Body mass index; CI, confidence intervals; FIB-4, Fibrosis-4 index; HDL-C, high-density lipoprotein cholesterol; HR, hazard ratio; MASLD, metabolic dysfunction-associated steatotic liver disease; TyG, triglyceride-glucose; WC, waist circumference