. Author manuscript; available in PMC: 2024 Jul 5.

Published in final edited form as: Ann Surg. 2022 Jul 6;277(6):e1239–e1246. doi: 10.1097/SLA.0000000000005450

TABLE 2.

Comparison and Validation of Predictive Performance of the Current Versus the Revised Classification in Unadjusted Cox Regression Models for OS

Subgroup and Unadjusted Cox Model	OS
Subgroup and Unadjusted Cox Model	AIC^*	Harrell’s C-index^†

Entire cohort (n=7195)
ypN	60782	0.587
r-ypN	60752	0.591
ypTNM	60628	0.610
r-ypTNM	60623	0.613
External validation, NEOCRTEC5010 (n=182)
ypN	665.20	0.682
r-ypN	651.24	0.701
ypTNM	669.91	0.688
r-ypTNM	663.45	0.699

The lower the AIC value is, the better the calibration.

^†

The higher the Harrell’s C-index is, the better the discrimination.

r-ypN indicates revised N stage defined by lymph node ratio; r-ypTNM, revised ypTNM by replacing pN stage with r-pN; ypN, pathologic N stage (AJCC-8); ypTNM, postneoadjuvant therapy staging group (AJCC-8).