Table 2.
Serum lipid pattern at baseline in patients who later converted to SSVD, AD, and mixed dementia as well as in stable SCI/MCI.
| Variable | SSVD (n = 15) | AD (n = 39) | Mixed dementia (n = 26) | Stable SCI/MCI (n = 249) | F-value | P-value between groups | Partial η2 |
|---|---|---|---|---|---|---|---|
| Total cholesterol (mmol/L) | 5.59 (1.05) | 6.03 (1.19) | 5.98 (0.66) | 5.74 (0.95) | 1.49 | 0.22 | 0.014 |
| LDL (mmol/L) | 3.52 (0.92) | 3.70 (0.95) | 3.57 (0.55) | 3.51 (0.89) | 0.58 | 0.63 | 0.005 |
| HDL (mmol/L) | 1.33 (0.31)a,b,c | 1.85 (0.54) | 1.92 (0.60) | 1.69 (0.47) | 5.77 | <0.001 | 0.051 |
| Triglycerides (mmol/L) | 1.63 (1.03) | 1.05 (0.38) | 1.08 (0.43) | 1.19 (0.63) | 2.37 | 0.07 | 0.021 |
| LDL / HDL ratio | 2.83 (1.02) | 2.15 (0.81) | 2.07 (0.81) | 2.27 (0.95) | 1.85 | 0.14 | 0.017 |
| Triglycerides / HDL ratio | 1.35 (1.09)a,b,c | 0.63 (0.34) | 0.68 (0.53) | 0.82 (0.62) | 4.68 | <0.01 | 0.042 |
Values are given as means (SD). All patients had subjective or objective mild cognitive impairment (SCI/MCI) at baseline. All patients (n = 329) had values for TC and TG, whereas 326 (99 %) of the patients had values for HDL and LDL. Differences across groups were assessed using analysis of variance (ANOVA) followed by post hoc analyses using the Bonferroni post hoc test. F-values and partial eta square (η2) values were calculated using ANOVA.
a
p < 0.05 vs. stable SCI/MCI.
b
p < 0.01 vs. AD.
c
p < 0.01 vs. mixed dementia.