Figure 2.

Proteomic changes in plasma samples of patients with viral sepsis compared to viral non sepsis

Orthogonal partial least squares-discriminant analysis (OPLS-DA) of proteins between viral sepsis and viral non-sepsis groups (A). Volcano plot displaying differential expression of protein levels between viral sepsis (VS) group and viral non-sepsis (VNS) group (B). Heatmaps demonstrating top 25 differentially expressed proteins (C). The significantly enriched KEGG pathways and the corresponding differentially expressed proteins (DEPs). The color intensity demonstrates log2 fold changes and the color denotes up (red) or down (blue) (D).