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. Author manuscript; available in PMC: 2024 Jul 5.
Published in final edited form as: Biomaterials. 2022 Mar 10;283:121457. doi: 10.1016/j.biomaterials.2022.121457

Fig. 3.

Fig. 3.

Delivery of PLG-Ag to KCs and LSECs results in Ag-specific upregulation of inhibitory molecule PD-L1. OT-II mice (n = 3) were injected with 2 mg of PLG-OVA or irrelevant PLG-PLP. After 24 h, liver non-parenchymal cells were isolated and analyzed by flow cytometry. (A) Histograms and (B) quantified median fluorescent intensity of costimulatory molecules CD80, CD86, and CD40, and coinhibitory molecule PD-L1 on KCs and LSECs. Statistical differences were determined by individual t-tests. Differences are indicated between PLG-OVA and PLG-PLP. Error bars represent SD and data are representative of 3 independent experiments.