Table 1. Selected predicted genes for experimental validation.
| Gene | AGAP007406 | AGAP002076 | AGAP009441 |
|---|---|---|---|
| Uniprot annotation | Q7PT29 (Elongation factor 1-alpha) | A7UVK8 (Heat shock 70kDa protein 1/8) | Q7PTN2 (Elongation factor 2) |
| Essentiality score | 0.38759 | 0.26499 | 0.60084 |
| CE prediction | Essential | Essential | Essential |
| OE prediction | Essential | Essential | Essential |
| Essential orthologs | 6 | 14 | 14 |
| Non-essential orthologs | 11 | 52 | 6 |
| Orthology Prediction | Non-essential | Non-essential | Essential |
| TPM (Mean) | 7919.616 | 3462.944 | 3025.191 |
| TPM (Median) | 8114.321 | 3602.958 | 3051.977 |
| TPM (25th Percentile) | 6072.29 | 2342.043 | 2166.012 |
| TPM (75 Percentile) | 10231.74 | 4560.174 | 4026.935 |
| Drosophila melanogaster Ortholog | FBgn0000557 | FBgn0266599 | FBgn0000559 |
| OGEE Essentiality of Drosophila melanogaster Ortholog | Conditionally essential | Conditionally essential | Essential |
Essentiality score is based on CLEARER prediction; Essential/Non-essential orthologs are based on OGEE and DEG database; CE prediction: Cellular essentiality prediction; OE prediction: Organism essentiality prediction.