FIG. 5.

Titers of MCMV mutants in salivary glands (A), lungs (B), spleens (C), livers (D), and kidneys (E) of the infected BALB/c mice. BALB/c-Byj mice were infected intraperitoneally with 10³ PFU of each virus. At 1, 3, 7, and 14 days postinfection, the animals (three mice per group) were sacrificed. The salivary glands, lungs, spleens, livers, and kidneys were collected and sonicated. The viral titers in the tissue homogenates were determined by standard plaque assays in NIH 3T3 cells. The limit of detection was 10 PFU/ml of the tissue homogenate. The viral titers represent the average obtained from triplicate experiments. The error bars indicate the standard deviation. Error bars that are not evident indicate that the standard deviation was less than or equal to the height of the symbols.