Table 1.

Demographic, Clinical, and Radiologic Characteristics of Patients With PPMS

Characteristics	Whole cohort
N	68
Age, ya,b	52.2 (9.1)
Male/female, % men	26/42 (38.0)
Disease duration, ya,c	6.2 (6.9)
Follow-up time, ya,d	9.6 (4.8)
EDSS at baseline	3.5 (2.5–5.5)
EDSS at 2 y	4.0 (3.0–6.5)
EDSS at 6 y	6.0 (5.0–7.0)
EDSS at last visit	6.3 (4.8–7.1)
Short-term progressors/nonprogressors, n (%)e	21 (33.9)/41 (66.1)
Medium-term progressors/nonprogressors, n (%)e	13 (22.4)/45 (77.6)
Long-term progressors/nonprogressors, n (%)	17 (25.0)/51 (75.0)
Relapses in the previous 3 mo, n (%)f	0 (0)
Treatment during follow-up, n (%)g	1 (1.5)
MRI findings, n (%)
Inflammatory	24 (35.0)
Noninflammatory	32 (47.0)
Unknown	12 (18.0)
IgM index	0.06 (0.03–0.14)
Qalb	5.8 (4.2–7.2)

Abbreviation: EDSS = Expanded Disability Status Scale.

Data are expressed as median (interquartile range) unless otherwise stated.

^aData are expressed as mean (SD).

^bRefers to age at sample collection.

^cRefers to the time between disease onset and sample collection.

^dRefers to the time between sample collection and the time of the last visit.

^eInformation missing in 6 (8.8%) and 10 (14.7%) patients, respectively.

^fRefers to the presence of relapses in the 3 mo before sample collection.

^gOne patient was treated with interferon-beta for 2 y after lumbar puncture.