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. 2023 Jun 28;15(4):714–728. doi: 10.1007/s12975-023-01169-x

Fig. 5.

Fig. 5

Validation of IL11 increased expression in the stroke ipsilateral hemisphere by immunohistochemistry. a IL11 is only detected in the ipsilateral hemisphere of mice subjected to stroke in the proximity of pericytes. b Location of the selected images. The infarct core is outlined. c Area fraction occupied by IL11 and PDGFR𝛽 signals. Data are presented as mean ± SEM. P = 0.028, paired t-test 95% confidence level (confidence intervals 0.01985 to 0.05979). Scale bar = 20 μm. d Orthogonal views showing IL11 expression in PDGFR𝛽 and CD13 expressing cells in the ipsilateral cortex and e 2D maximum projection of the merged channels. z stack = 24 μm; scale bar = 25 μm. Arrow points at IL11 signal