Table 2.

Univariate and multivariate analysis of the overall survival

Prognostic variables	Univariate analysis HR (95% CI)	P	multivariate analysis HR (95% CI)	P
Conditioning regimen (AD-BEAC vs. SD-BEAC)	0.446 (0.202–0.986)	0.046	0.432 (0.194–0.963)	0.040
Age (≤ 41 vs. > 41)	1.452 (0.692–3.047)	0.324	1.765 (0.751–4.149)	0.193
Disease type (B cell lymphoma vs. T- and NK-cell lymphoma)	1.871 (0.202–0.986)	0.101	1.894 (0.801–4.475)	0.146
Disease stage (I–II vs. III–IV)	1.131 (0.459–2.791)	0.789	0.810 (0.300–2.186)	0.677
IPI scores (1–3 vs. 4–5)	1.157 (0.534–2.506)	0.712	1.120 (0.458–2.738)	0.803
Time from diagnosis to ASCT (≤ 5 vs. > 5)	1.733 (0.819–3.664)	0.150	1.230 (0.515–2.938)	0.642
Chemotherapy cycles before ASCT (≤ 4 vs. > 4)	1.932 (0.913–4.085)	0.085	1.596 (0.616–4.134)	0.336
Disease status before ASCT (CR vs. PR)	3.132 (1.465–6.695)	0.003	2.033 (0.842–4.907)	0.115
Newly diagnosed or relapsed/refractory disease (newly diagnosed vs. relapsed/refractory disease)	2.846 (1.330–6.091)	0.007	1.770 (0.744–4.209)	0.197

HR hazard ratio, CI confidence interval, IPI international prognostic index, ASCT autologous stem cell transplantation