Fig. 3.

Relationship between DNA methylation age acceleration and longitudinal changes of liver fat content and related metabolic parameters. Comparison of the longitudinal changes in the levels of A liver fat content (LFC), B alanine transaminase (ALT), C aspartate transaminase (AST), D BMI, E triglycerides, F cholesterol, G systolic blood pressure, H fasting plasma glucose (FPG), and I post-load plasma glucose (PPG) between the participants with and without DNA methylation age acceleration. Linear correlations of DNA methylation age acceleration with changes in J LFC, K serum ALT, and L AST