Table 3.
Survival statistics for the effects of ERGO in C. elegans
| Group | Log-rank P-value | Median (days) | Change in mediana | Average (days) | Change in averageb | P90c (days) | Change in P90d |
|---|---|---|---|---|---|---|---|
| Lifespan | |||||||
| Control | 14.5 | 14.0 | 22.0 | ||||
| 5 mM ERGO | < 0.1 | 17.0 | 17.2% | 15.5 | 10.6% | 22.0 | 0.0% |
| 10 mM ERGO | < 0.01 | 19.0 | 31.0% | 18.4 | 30.4% | 23.5 | 6.8% |
| Non-frailty span | |||||||
| Control | 12.5 | 11.4 | 19.0 | ||||
| 5 mM ERGO | < 0.1 | 13.5 | 8.0% | 12.6 | 10.6% | 19.0 | 0.0% |
| 10 mM ERGO | < 0.05 | 15.5 | 24.0% | 14.8 | 30.4% | 20.5 | 7.9% |
aChange in median was calculated as ([median for ERGO − median for control]/median for control) × 100
bChange in average was calculated as ([average for ERGO − average for control]/average for control) × 100
cP90 is the age at which 90% of the mice had died
dChange in P90 is presented as the percentage difference between ERGO and control groups